Lipoxin A4

Cat. No.: IBDI-431415

Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties. Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways. Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC50 value of 25.74 nM.

Product Details

Target	Interleukin Related | Endogenous Metabolite
Molecular Weight	352.47
Appearance	Liquid
Synonyms	LXA4
SMILES	CCCCC[[email protected]](O)/C=C/C=C\C=C\C=C\[[email protected]@H](O)[[email protected]@H](O)CCCC(O)=O
Purity	≥98.0%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Solution, -20°C, 2 years
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.