LSD1/ER-IN-1

Cat. No.: IBDI-437594

LSD1/ER-IN-1 (compound 11g) is a potent ER and LSD1 inhibitor, with an IC50 of 1.55 μM (LSD1). LSD1/ER-IN-1 has high affinity selectivity for ERα protein, with α/β ratio of 7.11. LSD1/ER-IN-1 shows good antiproliferative activity against MCF-7 breast cancer cells, with an IC50 of 8.79 μM.

Product Details

Target	Histone Demethylase | Estrogen Receptor/ERR | Apoptosis
Molecular Weight	455.46
SMILES	O=S([[email protected]]1C[[email protected]@H]2C(C3=CC=C(C=C3)O)=C([[email protected]]1O2)C4=CC=C(C=C4)O)(OC5=NC(F)=CC=C5)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.