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* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Lurbinectedin

Cat. No.: IBDI-434637

Lurbinectedin (PM01183) is a DNA minor groove covalent binder with potent anti-tumour activity; inhibits RMG1 and RMG2 cell growth with IC50 values of 1.25 and 1.16 nM, respectively.

Size (Solid):

Product Details

Target DNA Alkylator/Crosslinker | DNA/RNA Synthesis
Molecular Weight 784.87
Appearance Solid
Synonyms PM01183, LY-01017
SMILES O[[email protected]@H]([[email protected]@](CC1=CC(C)=C2OC)([H])N(C)[[email protected]]3([H])C1=C2O)N([[email protected]](COC4=O)([H])C5=C(OCO6)C6=C7C)[[email protected]@]3([H])[[email protected]@](SC[[email protected]@]4(NCC8)C9=C8C%10=CC(OC)=CC=C%10N9)([H])C5=C7OC(C)=O
Purity 99.80%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years
In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.