LY-411575

Products

Antibodies for IBD Research
Assay Kits for IBD Research
Inhibitors & Activators for IBD Research
Proteins & Peptides for IBD Research
Reported Gene Cell Lines for IBD Research

Inquiry

Cat. No.: IBDI-436950

LY-411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), and also inhibits Notch S3 cleavage with IC50 of 0.39 nM.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	γ-secretase \| Notch \| Apoptosis
Molecular Weight	479.48
Appearance	Solid
SMILES	O=C1[[email protected]@H](NC([[email protected]@H](NC([[email protected]](C2=CC(F)=CC(F)=C2)O)=O)C)=O)C3=CC=CC=C3C(C=CC=C4)=C4N1C
Purity	≥98.0%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.