Cat. No.: IBDA-433449
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Online InquiryTarget Information
| Target Name | M6PR (cation dependent) |
| Uniprot ID | P20645 |
| Cellular Localization | Lysosome membrane. |
| Immunogen | Synthetic peptide corresponding to Human M6PR (cation dependent) aa 250 to the C-terminus (C terminal). |
| Function | Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. |
Product Details
| Description | Rabbit monoclonal antibody to M6PR (cation dependent). |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse, Rat, Human |
| Immunogen | Synthetic peptide corresponding to Human M6PR (cation dependent) aa 250 to the C-terminus (C terminal). |
| Positive Control | WB: HAP1, A549, and Human uterus lysates ICC/IF: HeLa cell lysate Flow Cyt (Intra): A549 cells |
| Application | Flo, ICC/IF, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.20 Preservative: 0.01% Sodium Azide Constituent: 40% Glycerol, 59% PBS, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |