Cat. No.: IBDA-434164
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Online InquiryTarget Information
| Target Name | M6PR (cation independent) |
| Uniprot ID | P11717 |
| Cellular Localization | Lysosome membrane. Colocalized with DPP4 in internalized cytoplasmic vesicles adjacent to the cell surface. |
| Immunogen | Synthetic peptide. |
| Function | Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4. |
Product Details
| Description | Rabbit monoclonal antibody to M6PR (cation independent) - BSA and Azide Free. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse, Rat, Human |
| Immunogen | Synthetic peptide. |
| Positive Control | Jurkat, 293T, C6, PC-12, NIH/3T3 and Caco-2 cell lysates. Human papillary carcinoma, thyroid and tonsil tissue. Mouse heart, kidney, colon and spleen tissue. Rat colon tissue . |
| Application | Flo, ICC/IF, IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C |
| Storage Buffer | pH: 7.20 Constituent: PBS |
| Handling | Do not freeze. |