Cat. No.: IBDA-434158
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Online InquiryTarget Information
| Target Name | M6PR (cation independent) |
| Uniprot ID | P11717 |
| Cellular Localization | Lysosome membrane. Colocalized with DPP4 in internalized cytoplasmic vesicles adjacent to the cell surface. |
| Immunogen | Recombinant Vaccinia virus encoding CD222. |
| Function | Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4. |
Product Details
| Description | PE Mouse monoclonal antibody to M6PR (cation independent). |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Size exclusion |
| Isotype | IgG1 |
| Conjugation | PE |
| Reactivity | Human |
| Immunogen | Recombinant Vaccinia virus encoding CD222. |
| Positive Control | Flow Cyt: Human blood cells |
| Application | Flo, Flo |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C |
| Storage Buffer | pH: 7.4 Preservative: 0.097% Sodium Azide Constituent: 0.2% BSA, 0.2% PBS0.2% BSA (high-grade protease free) |