M6PR (cation independent) Monoclonal Antibody

Target Information

Target Name	M6PR (cation independent)
Uniprot ID	P11717
Cellular Localization	Lysosome membrane. Colocalized with DPP4 in internalized cytoplasmic vesicles adjacent to the cell surface.
Immunogen	Synthetic peptide.
Function	Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.

Product Details

Description	APC Rabbit monoclonal antibody to M6PR (cation independent) - Lysosome Membrane Marker.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	APC
Reactivity	Human
Immunogen	Synthetic peptide.
Positive Control	Flow Cyt (Intra): HeLa cells
Application	Flo

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Upon delivery aliquot. Store at 4 °C. Store in the dark
Storage Buffer	pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: 1% BSA, PBS
Handling	Do not freeze.