Cat. No.: IBDA-434232
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Online InquiryTarget Information
| Target Name | Macrophage Inflammatory Protein 1 Alpha/CCL3 |
| Uniprot ID | P10147 |
| Cellular Localization | Secreted. |
| Immunogen | Recombinant fragment. |
| Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). |
Product Details
| Description | Rabbit monoclonal antibody to MIP-1 alpha/CCL3. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant fragment. |
| Positive Control | ICC/IF: THP-1 cells treated with 80nM TPA overnight, then treated with 100ng/ml LPS for 3h and together with 300ng/ml BFA for another 3h. Flow: THP-1 cells treated with 80nM TPA overnight, then treated with 100ng/ml LPS for 3h and together with 300ng/ml BFA for another 3h. |
| Application | Flo, ICC/IF |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: PBS, 40% Glycerol, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |