MAdCAM1 Monoclonal Antibody - BSA and Azide Free

Target Information

Target Name	MAdCAM1
Uniprot ID	Q13477
Cellular Localization	Membrane.
Immunogen	Recombinant fragment.
Function	Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.

Product Details

Description	Rabbit monoclonal antibody to MAdCAM1 - BSA and Azide Free.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Mouse
Immunogen	Recombinant fragment.
Positive Control	WB: TNF alpha treated bEnd.3 whole cell lysate. HEK-293 transfected with a mouse MAdCAM1 (WT) expression vector containing a myc-His-tag® whole cell lysate. IHC-P: Mouse jejunum tissue. IP: Mouse colon tissue lysate.
Application	IHC-P, IP, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at 4 °C
Storage Buffer	pH: 7.2 Constituent: 100% PBS
Handling	Do not freeze.