Cat. No.: IBDA-431973
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Online InquiryTarget Information
| Target Name | MAdCAM1 |
| Uniprot ID | Q13477 |
| Cellular Localization | Membrane. |
| Immunogen | Synthetic peptide within Human MAdCAM1 aa 1-100 (extracellular). |
| Function | Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding. |
Product Details
| Description | Rabbit monoclonal antibody to MAdCAM1. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Tissue culture supernatant |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide within Human MAdCAM1 aa 1-100 (extracellular). |
| Positive Control | HeLa, HUVEC, and ECV-304 cell lysates |
| Application | WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at -20 °C |
| Storage Buffer | pH: 7.20 Preservative: 0.01% Sodium Azide Constituent: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue Culture Supernatant |
| Handling | Avoid freeze-thaw cycles. |