MAdCAM1 Monoclonal Antibody

Target Information

Target Name	MAdCAM1
Uniprot ID	Q13477
Cellular Localization	Membrane.
Immunogen	Mouse Endothelial cells.
Function	Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.

Product Details

Description	Rat monoclonal antibody to MAdCAM1.
Host Species	Rat
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG2
Conjugation	Unconjugated
Reactivity	Mouse
Immunogen	Mouse Endothelial cells.
Application	Flo, IHC-Fr, IHC-P, Inhibition, IP

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Upon delivery aliquot. Store at -20 °C or -80 °C
Storage Buffer	Constituent: PBS
Handling	Avoid freeze-thaw cycles.