Cat. No.: IBDA-431971
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Online InquiryTarget Information
| Target Name | MAdCAM1 |
| Uniprot ID | Q13477 |
| Cellular Localization | Membrane. |
| Immunogen | Recombinant fragment corresponding to Human MAdCAM1 aa 1-350 (extracellular). |
| Function | Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding. |
Product Details
| Description | Rabbit polyclonal antibody to MAdCAM1. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Protein G purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant fragment corresponding to Human MAdCAM1 aa 1-350 (extracellular). |
| Positive Control | WB: HepG2 whole cell lysate. ICC/IF: HepG2 cells. |
| Application | ICC/IF, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.40 Constituent: 50% Glycerol, PBS, 0.03% Proclin 300 |
| Handling | Avoid freeze-thaw cycles. |