Cat. No.: IBDA-431966
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Online InquiryTarget Information
| Target Name | MAdCAM1 |
| Uniprot ID | Q13477 |
| Cellular Localization | Membrane. |
| Immunogen | Synthetic peptide within Human MAdCAM1 aa 50-150 conjugated to keyhole limpet haemocyanin. |
| Function | Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding. |
Product Details
| Description | Rabbit polyclonal antibody to MAdCAM1. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse |
| Immunogen | Synthetic peptide within Human MAdCAM1 aa 50-150 conjugated to keyhole limpet haemocyanin. |
| Positive Control | Mouse intestine tissue. |
| Application | IHC-P |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.09% Sodium Azide Constituent: 1% BSA, 50% Glycerol |
| Handling | Avoid freeze-thaw cycles. |