MAEA Polyclonal Antibody

Target Information

Target Name	MAEA
Uniprot ID	Q7L5Y9
Cellular Localization	Nucleus matrix. Cell membrane. Cytoplasm, cytoskeleton. Localized as nuclear speckled-like pattern.
Immunogen	Recombinant fragment (His-T7-tag) corresponding to Human MAEA aa 100 to the C-terminus.
Function	Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA-mediated contact inhibits erythroid cells apoptosis. Participates to erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.

Product Details

Description	Rabbit polyclonal antibody to MAEA.
Host Species	Rabbit
Clonality	Polyclonal
Purity	Immunogen affinity purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Mouse, Human
Immunogen	Recombinant fragment (His-T7-tag) corresponding to Human MAEA aa 100 to the C-terminus.
Positive Control	WB: Recombinant human MAEA protein. Mouse cerebrum and pancreas lysates. IHC-P: Human breast cancer, skin cancer, cerebrum, colorectal cancer, bile duct cancer and kidney tissues.
Application	IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: PBS, 50% Glycerol
Handling	Avoid freeze-thaw cycles.