MAEA Polyclonal Antibody

Target Information

Target Name	MAEA
Uniprot ID	Q7L5Y9
Cellular Localization	Nucleus matrix. Cell membrane. Cytoplasm, cytoskeleton. Localized as nuclear speckled-like pattern.
Immunogen	Recombinant fragment, corresponding to a region within amino acids 169-396 of Human MAEA.
Function	Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA-mediated contact inhibits erythroid cells apoptosis. Participates to erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.

Product Details

Description	Rabbit polyclonal antibody to MAEA.
Host Species	Rabbit
Clonality	Polyclonal
Purity	Immunogen affinity purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Recombinant fragment, corresponding to a region within amino acids 169-396 of Human MAEA.
Positive Control	HCT116 cell line. HepG2 whole cell lysate. HeLa cells
Application	ICC/IF, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Upon delivery aliquot. Store at -20 °C or -80 °C
Storage Buffer	pH: 7 Preservative: 0.01% Thimerosal (Merthiolate) Constituent: 1.21% Tris, 0.75% Glycine, 20% Glycerol
Handling	Avoid freeze-thaw cycles.