Mcl-1 inhibitor 3

Cat. No.: IBDI-433409

Mcl-1 inhibitor 3 (compound 1) is a highly potent and orally activate macrocyclic Mcl-1 inhibitor (Ki= 0.061 nM; IC50=19 nM in an OPM-2 cell viability assay). Mcl-1 inhibitor 3 shows good pharmacokinetic properties and excellent in vivo efficacy without toxicity..

Product Details

Target	Bcl-2 Family
Molecular Weight	820.38
SMILES	ClC1=CC(CCC2)=C(C=C1)[[email protected]]2(CO3)CN(C[[email protected]]4[[email protected]@H](CC4)[[email protected]@H](OCCN5CC(F)(F)C5)/C=C/CCN(C)C6=O)C7=C3C=CC([[email protected]@](O)(C(NS(=O)(N(C)C)=O)=O)C6)=C7

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.