McMMAF

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Cat. No.: IBDI-434893

McMMAF is a protective group (maleimidocaproyl)-conjugated MMAF, which is a potent tubulin polymerization inhibitor. McMMAF can be used as a agent-linker for antibody-drug conjugates (ADC). McMMAF is uncleavable, and must be internalized and degraded within a cell, releasing cysteine-McMMAF as the active agent.

Size (Solid):

Product Details

Target	Drug-Linker Conjugates for ADC
Molecular Weight	925.16
Appearance	Solid
Synonyms	Maleimidocaproyl monomethylauristatin F
SMILES	O=C([[email protected]](C)[[email protected]]([[email protected]]1([H])CCCN1C(C[[email protected]@H](OC)[[email protected]@]([H])(N(C([[email protected]](C(C)C)NC([[email protected]](C(C)C)N(C)C(CCCCCN2C(C=CC2=O)=O)=O)=O)=O)C)[[email protected]@H](C)CC)=O)OC)N[[email protected]](C(O)=O)CC3=CC=CC=C3
Purity	99.53%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.