Cat. No.: IBDA-434075
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Online InquiryTarget Information
| Target Name | MCP1 |
| Uniprot ID | P13500 |
| Cellular Localization | Secreted. |
| Immunogen | Synthetic peptide. |
| Function | Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. |
Product Details
| Description | Rabbit monoclonal antibody to MCP1. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Positive Control | WB: THP-1 treated with PMA, LPS, and BFA whole cell lysate. ICC/IF: THP-1 cells treated with PMA, LPS, and BFA, wild-type and MCP1 knockout HeLa cells treated with TNF-alpha (20ng/mL, 6 hours). Flow Cyt (Intra): THP-1 treated with PMA, LPS, and BFA. IP: THP-1 treated with PMA, LPS, and BFA whole cell lysate. |
| Application | Flo, ICC/IF, IP, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: PBS, 40% Glycerol, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |