Cat. No.: IBDA-431782
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Online InquiryTarget Information
| Target Name | MCPIP1 |
| Uniprot ID | Q5D1E8 |
| Cellular Localization | Cytoplasm. Nucleus. |
| Immunogen | Recombinant fragment, corresponding to a sequence within amino acids 291-474 of Human MCPIP1. |
| Function | Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA (By similarity). Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19. |
Product Details
| Description | Rabbit polyclonal antibody to MCPIP1. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant fragment, corresponding to a sequence within amino acids 291-474 of Human MCPIP1. |
| Positive Control | WB: HEK-293T, A431,whole cell lysate. IF: HeLa cells. |
| Application | ICC/IF, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7 Preservative: 0.025% Proclin 300 Constituent: 79% PBS, 20% Glycerol |
| Handling | Avoid freeze-thaw cycles. |