MCPIP1 Polyclonal Antibody

Target Information

Target Name	MCPIP1
Uniprot ID	Q5D1E8
Cellular Localization	Cytoplasm. Nucleus.
Immunogen	Recombinant fragment (GST-tag) within Human MCPIP1 (internal sequence).
Function	Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA (By similarity). Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19.

Product Details

Description	Rabbit polyclonal antibody to MCPIP1.
Host Species	Rabbit
Clonality	Polyclonal
Purity	Immunogen affinity purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Recombinant fragment (GST-tag) within Human MCPIP1 (internal sequence).
Positive Control	K562 cell lysate. Human colon cancer tissue.
Application	IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.4 Preservative: 0.05% Sodium Azide Constituent: 50% Glycerol, 49% PBS
Handling	Avoid freeze-thaw cycles.