Cat. No.: IBDA-431787
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Online InquiryTarget Information
| Target Name | MCPIP1 |
| Uniprot ID | Q5D1E8 |
| Cellular Localization | Cytoplasm. Nucleus. |
| Immunogen | Synthetic peptide corresponding to Human MCPIP1 aa 300-400 conjugated to keyhole limpet haemocyanin. |
| Function | Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA (By similarity). Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19. |
Product Details
| Description | Rabbit polyclonal antibody to MCPIP1. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide corresponding to Human MCPIP1 aa 300-400 conjugated to keyhole limpet haemocyanin. |
| Positive Control | IHC-P: Human adrenal gland tissue. WB: HepG2 cell lysate. Flow Cyt (Intra): HepG2 cells. |
| Application | Flo, IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.4 Preservative: 0.09% Sodium Azide Constituent: PBS |
| Handling | Avoid freeze-thaw cycles. |