Mevociclib

Products

Inquiry

Cat. No.: IBDI-435649

Mevociclib (SY-1365) is a potent and first-in-class selective CDK7 inhibitor, with a Ki of 17.4 nM. Mevociclib exhibits anti-proliferative and apoptotic effects in solid tumor cell lines. Mevociclib possesses anti-tumor activity in hematological and multiple aggressive solid tumors.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	CDK
Molecular Weight	587.12
Appearance	Solid
Synonyms	SY-1365
SMILES	O=C(C1=NC=C(NC(/C=C/CN(C)C)=O)C=C1)N[[email protected]@]2(C)CCC[[email protected]@H](NC3=NC=C(Cl)C(C4=CNC5=C4C=CC=C5)=N3)C2
Purity	99.27%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.