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* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Milademetan

Cat. No.: IBDI-436226

Milademetan (DS-3032) is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS-3032) induces G1 cell cycle arrest, senescence and apoptosis.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target MDM-2/p53 | E1/E2/E3 Enzyme | Apoptosis
Molecular Weight 618.53
Appearance Solid
Synonyms DS-3032
SMILES O=C(NC1=CC(Cl)=CC=C21)[[email protected]]32C4(CCC(C)(C)CC4)N[[email protected]@H](C(N[[email protected]@H]5CC[[email protected]@H](C(N)=O)OC5)=O)[[email protected]@H]3C6=CC=NC(Cl)=C6F
Purity 98.77%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years; 4°C/2 years
In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.