Mitotane-13C6

Cat. No.: IBDI-433368

Mitotane- 13C6 is the 13C labeled Mitotane. Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions.

Product Details

Target	Apoptosis
Molecular Weight	326.00
Synonyms	2,4′-DDD-13C6, o,p'-DDD-13C6
SMILES	ClC(Cl)C([13C]1=[13CH][13CH]=[13C]([13CH]=[13CH]1)Cl)C2=C(C=CC=C2)Cl

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.