ML334

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Cat. No.: IBDI-435478

ML334 is a potent, cell permeable activator of NRF2 by inhibition of Keap1-NRF2 protein-protein interaction. ML334 binds to Keap1 Kelch domain with a Kd of 1 μM. ML334 stimulates NRF2 expression and nuclear translocation and induces antioxidant response elements (ARE) activity.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	Keap1-Nrf2
Molecular Weight	446.50
Appearance	Solid
Synonyms	LH601A
SMILES	O=C(C1=CC=CC=C1C2=O)N2C[[email protected]@H]3C4=CC=CC=C4CCN3C([[email protected]]5[[email protected]](CCCC5)C(O)=O)=O
Purity	99.82%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.