MMAF-OMe

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Cat. No.: IBDI-432807

MMAF-Ome, an antitubulin agent, is also an ADC cytotoxin. MMAF-Ome inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4 -) cell lines, respectively.

Size (Solid):

Product Details

Target	ADC Cytotoxin
Molecular Weight	745.99
Appearance	Solid
Synonyms	Monomethyl auristatin F methyl ester
SMILES	CC[[email protected]](C)[[email protected]@H]([[email protected]@H](CC(N1[[email protected]@H](CCC1)[[email protected]@H]([[email protected]@H](C)C(N[[email protected]](C(OC)=O)CC2=CC=CC=C2)=O)OC)=O)OC)N(C([[email protected]](C(C)C)NC([[email protected]](C(C)C)NC)=O)=O)C
Purity	96.68%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years *The compound is unstable in solutions, freshly prepared is recommended.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.