Mollugin

Cat. No.: IBDI-431211

Mollugin is an orally active and potent NF-κB inhibitor. Mollugin induces S-phase arrest of HepG2 cells, and increased intracellular reactive oxygen species (ROS) levels. Mollugin induces DNA damage in HepG2 cells, as well as an increase in the expression of p-H2AX. Mollugin shows anti-cancer effect by inhibiting TNF-α-induced NF-κB activation. Mollugin enhances the osteogenic action of BMP-2 (bone morphogenetic protein 2) via the p38-Smad signaling pathway.

Product Details

Target	NF-κB | Reactive Oxygen Species | Apoptosis | VEGFR | c-Myc
Molecular Weight	284.31
Appearance	Solid
SMILES	O=C(C1=C(C=CC(C)(C)O2)C2=C3C=CC=CC3=C1O)OC
Structure Classification	Terpenoids>Sesquiterpenes Phenols>Monophenols
Purity	99.48%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.