Mouse IL-34 ELISA Kit

Overview

Sample Type	Cell culture supernatant, Serum, Cell Lysate, Hep Plasma, EDTA Plasma
Detection Method	Colorimetric
Assay Type	Sandwich (quantitative)
Assay Time	3 h 30 min
Assay Duration	Multiple steps standard assay
Product Type	Macrophage / Inflamm.
Sensitivity	< 10 pg/ml
Range	62.5 pg/ml - 4000 pg/ml
Species Reactivity	Reacts with: Mouse
Platform	Pre-coated microplate (12 x 8 well strips)

Target

Function	Cytokine that promotes the differentiation and viability of monocytes and macrophages. Stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. Ligand for colony-stimulating factor-1 receptor CSF1R.
Tissue Specificity	Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level). Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon.
Sequence Similarities	Belongs to the IL-34 family.
Cellular Localization	Secreted.

Storage & Handling

Storage

Store at +4°C. Please refer to protocols.