Mouse P-Selectin Antibody Pair - BSA and Azide free

Overview

Assay Type	ELISA set
Product Type	Cell Type Markers
Range	15.62 pg/ml - 1000 pg/ml
Species Reactivity	Reacts with: Mouse
Platform	Reagents
Application	Sandwich ELISA

Properties

Carrier Free

Yes

Target

Function	Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1.
Tissue Specificity	Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
Sequence Similarities	Belongs to the selectin/LECAM family. Contains 1 C-type lectin domain. Contains 1 EGF-like domain. Contains 9 Sushi (CCP/SCR) domains.
Cellular Localization	Membrane.

Storage & Handling

Storage	Store at +4°C.
Storage Buffer	Constituent: 100% PBS