Cat. No.: IBDAK-620245
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| Sample Type | Cell culture supernatant, Serum, Cell culture extracts, Hep Plasma, EDTA Plasma, Cit plasma |
| Detection Method | Colorimetric |
| Assay Type | Sandwich (quantitative) |
| Assay Time | 1 h 30 min |
| Assay Duration | One step assay |
| Product Type | Secreted Molecules |
| Sensitivity | 7.8 |
| Range | 93.73 pg/ml - 6000 pg/ml |
| Species Reactivity | Reacts with: Mouse Does not react with: Cow |
| Platform | Pre-coated microplate (12 x 8 well strips) |
Target
| Function | Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling.Granulin-4 promotes proliferation of the epithelial cell line A431 in culture while granulin-3 acts as an antagonist to granulin-4, inhibiting the growth. |
| Tissue Specificity | In myelogenous leukemic cell lines of promonocytic, promyelocytic, and proerythroid lineage, in fibroblasts, and very strongly in epithelial cell lines. Present in inflammatory cells and bone marrow. Highest levels in kidney. |
| Sequence Similarities | Belongs to the granulin family. |
| Cellular Localization | Secreted. |
Storage & Handling
| Storage | Store at -20°C. Please refer to protocols. |