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MR22

Cat. No.: IBDI-433678

MR22 is a potent pan-SIK (salt-inducible kinase) inhibitor. MR22 no longer exhibits activity on STE group kinases and displays excellent selectivity in a representative kinase panel. MR22-dependent SIK inhibition led to centrosome dissociation and subsequent cell-cycle arrest in ovarian cancer cells.

Size (Solid):

Product Details

Target Salt-inducible Kinase (SIK)
Molecular Weight 359.37
SMILES CNC1=NC=C2C=C(C(N(C2=N1)CCCCN)=O)C3=C(C=CC(F)=C3)F

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.