MRTX-1257-d6

Cat. No.: IBDI-431670

MRTX-1257-d6 is the deuterium labeled MRTX-1257 (HY-114436). MRTX-1257 is a selective, irreversible, covalent and orally active KRAS G12C inhibitor, with an IC50 of 900 pM for KRAS dependent ERK phosphorylation in H358 cells.

Product Details

Target	Isotope-Labeled Compounds
Molecular Weight	571.75
Synonyms	MRTX-1257-d6
SMILES	[2H]C([2H])([2H])N(CCC1)[[email protected]@H]1COC2=NC(N3C[[email protected]@H](N(CC3)C(C=C)=O)CC#N)=C4C(CN(C5=CC=CC6=C5C(C([2H])([2H])[2H])=CC=C6)CC4)=N2

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.