Cat. No.: IBDI-436490
MS645 is a bivalent BET bromodomains (BrD) inhibitor with a Ki of 18.4 nM for BRD4-BD1/BD2. MS645 spatially constrains bivalent inhibition of BRD4 BrDs resulting in a sustained repression of BRD4 transcriptional activity in solid-tumor cells.
Size (Solution): 10 mM * 1 mL in DMSO
Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution
Size (Solid): 5 mg 10 mg 25 mg 50 mg 100 mg 200 mg 500 mg
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