MyD88 Monoclonal Antibody

Target Information

Target Name	MyD88
Uniprot ID	Q99836
Cellular Localization	Cytoplasm.
Immunogen	Recombinant full length protein corresponding to Human MyD88.
Function	Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway.

Product Details

Description	Mouse monoclonal antibody to MyD88.
Host Species	Mouse
Clonality	Monoclonal
Purity	Affinity purified
Isotype	IgG2a
Conjugation	Unconjugated
Reactivity	Human, Recombinant fragment
Immunogen	Recombinant full length protein corresponding to Human MyD88.
Positive Control	WB: HEK293T cell lysate transfected with pCMV6-ENTRY MyD88 cDNA. Jerkat, and MOLT4 cell lysates. Flow Cyt (Intra): HEK293T cells transfected with pCMV6-ENTRY MyD88 overexpression plasmid. HeLa and Jurkat cells. ICC/IF: COS7 cells transiently transfected by pCMV6-ENTRY MyD88. HeLa and Jurkat cells.
Application	Flo, ICC/IF, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Upon delivery aliquot. Store at -20 °C
Storage Buffer	pH: 7.30 Preservative: 0.02% Sodium Azide Constituent: 1% BSA, 50% Glycerol, PBS
Handling	Avoid freeze-thaw cycles.