Cat. No.: IBDA-431544
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Online InquiryTarget Information
| Target Name | MyD88 |
| Uniprot ID | Q99836 |
| Cellular Localization | Cytoplasm. |
| Immunogen | Synthetic peptide, corresponding to amino acids 50-100 of Human MyD88. |
| Function | Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. |
Product Details
| Description | Mouse monoclonal antibody to MyD88. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Protein G purified |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide, corresponding to amino acids 50-100 of Human MyD88. |
| Positive Control | human ovary, human prostate and Jurkat cell lysates and CF-7 cells. Flow Cyt (Intra): Jurkat cells |
| Application | Flo, ICC/IF, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Upon delivery aliquot. Store at -20 °C |
| Storage Buffer | pH: 7.4 Preservative: 0.05% Sodium Azide Constituent: PBS, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |