Cat. No.: IBDA-431543
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Online InquiryTarget Information
| Target Name | MyD88 |
| Uniprot ID | Q99836 |
| Cellular Localization | Cytoplasm. |
| Immunogen | Synthetic peptide. |
| Function | Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. |
Product Details
| Description | Rabbit monoclonal antibody to MyD88. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Positive Control | Human kidney tissue. Jurkat, Molt-4, HepG2, K562, Raji cell lysates. Flow Cyt (Intra): HAP1-WT cells |
| Application | Flo, ICC/IF, IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.20 Preservative: 0.01% Sodium Azide Constituent: 40% Glycerol, 0.05% BSA, 59% PBS |
| Handling | Avoid freeze-thaw cycles. |