Cat. No.: IBDA-431539
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Online InquiryTarget Information
| Target Name | MyD88 |
| Uniprot ID | Q99836 |
| Cellular Localization | Cytoplasm. |
| Immunogen | Synthetic peptide within Human MyD88 aa 150-250 (internal sequence). |
| Function | Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. |
Product Details
| Description | Rabbit polyclonal antibody to MyD88. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Rat, Human |
| Immunogen | Synthetic peptide within Human MyD88 aa 150-250 (internal sequence). |
| Positive Control | WB: Rat spleen, thymus tissue lysate. Jurkat, Raji cell lysate. IHC-P: Human tonsil tissue. |
| Application | IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | Preservatives: 0.025% Thimerosal (Merthiolate), 0.025% Sodium Azide Constituent: 2.5% BSA, 0.1% Dibasic Monohydrogen Sodium Phosphate, 0.45% Sodium Chloride |
| Handling | Avoid freeze-thaw cycles. |