Cat. No.: IBDA-431537
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Online InquiryTarget Information
| Target Name | MyD88 |
| Uniprot ID | Q99836 |
| Cellular Localization | Cytoplasm. |
| Immunogen | Synthetic peptide corresponding to Human MyD88 aa 279-296 (C terminal). |
| Function | Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. |
Product Details
| Description | Rabbit polyclonal antibody to MyD88. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide corresponding to Human MyD88 aa 279-296 (C terminal). |
| Positive Control | WB: HEK293, HT29, K562, HepG2, A549 and Jurkat whole cell lysate. ICC/IF: Jurkat and K562 cells. |
| Application | ICC/IF, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Upon delivery aliquot. Store at -20 °C or -80 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.02% Sodium Azide |
| Handling | Avoid freeze-thaw cycles. |