Cat. No.: IBDA-431534
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Online InquiryTarget Information
| Target Name | MyD88 |
| Uniprot ID | Q99836 |
| Cellular Localization | Cytoplasm. |
| Immunogen | Synthetic peptide corresponding to Human MyD88 aa 250 to the C-terminus (internal sequence) (Cysteine residue). |
| Function | Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. |
Product Details
| Description | Biotin Goat polyclonal antibody to MyD88. |
| Host Species | Goat |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Biotin |
| Reactivity | Human |
| Immunogen | Synthetic peptide corresponding to Human MyD88 aa 250 to the C-terminus (internal sequence) (Cysteine residue). |
| Positive Control | Human thymus lysate. |
| Application | WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C. Store in the dark |
| Storage Buffer | pH: 7.30 Preservative: 0.02% Sodium Azide Constituent: 99% Tris Buffered Saline, 0.5% BSA |
| Handling | Avoid freeze-thaw cycles. |