Cat. No.: IBDA-431538
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Online InquiryTarget Information
Target Name | MyD88 |
Uniprot ID | Q99836 |
Cellular Localization | Cytoplasm. |
Immunogen | Synthetic peptide: C-IKYKAM KKEFP , corresponding to Internal sequence amino acids 255-265 of Human MyD88. |
Function | Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. |
Product Details
Description | Goat polyclonal antibody to MyD88. |
Host Species | Goat |
Clonality | Polyclonal |
Purity | Immunogen affinity purified |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Mouse, Human |
Immunogen | Synthetic peptide: C-IKYKAM KKEFP , corresponding to Internal sequence amino acids 255-265 of Human MyD88. |
Positive Control | Human T cell line MOLT4 cell lysate. Human thymus lysate. Human tonsil tissue sections. |
Application | Flo, ICC, IHC-P, WB |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Upon delivery aliquot. Store at -20 °C |
Storage Buffer | pH: 7.30 Preservative: 0.02% Sodium Azide Constituent: 0.5% Tris Buffered Saline, 0.5% BSA |
Handling | Avoid freeze-thaw cycles. |