Cat. No.: IBDAK-620185
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Online InquiryOverview
| Sample Type | Cell Lysate |
| Detection Method | Fluorescent |
| Assay Type | Enzyme activity |
| Product Type | Macrophage / Inflamm. |
| Sensitivity | < 0.1 mU/ml |
| Species Reactivity | Reacts with: Mammals, Other species |
| Platform | Microplate reader |
Target
| Function | Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. |
| Sequence Similarities | Belongs to the peroxidase family. XPO subfamily. |
| Cellular Localization | Lysosome. |
Storage & Handling
| Storage | Store at +4°C. |
| Storage Buffer | Constituent: 100% PBS |