MZ 1

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Inquiry

Cat. No.: IBDI-432884

MZ 1 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. MZ 1 potently and rapidly induces reversible, long-lasting, and selective removal of BRD4 over BRD2 and BRD3. Kds of 382/120, 119/115, and 307/228 nM for BRD4 BD1/2, BRD3 BD1/2, and BRD2 BD1/2, respectively.

Size (Solid):

Product Details

Target	PROTACs \| Epigenetic Reader Domain
Molecular Weight	1002.64
Appearance	Solid
SMILES	CC1=C(C)SC2=C1C(C3=CC=C(Cl)C=C3)=N[[email protected]@H](CC(NCCOCCOCCOCC(N[[email protected]@H](C(C)(C)C)C(N4[[email protected]@H](C[[email protected]@H](O)C4)C(NCC5=CC=C(C6=C(N=CS6)C)C=C5)=O)=O)=O)=O)C7=NN=C(C)N27
Purity	99.43%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.