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Necrostatin-1

Cat. No.: IBDI-435013

Necrostatin-1 (Nec-1) is a potent and cross the blood-brain barrier necroptosis inhibitor with an EC50 of 490 nM in Jurkat cells. Necrostatin-1 inhibits RIP1 kinase (EC50=182 nM). Necrostatin-1 is also an IDO inhibitor.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target RIP kinase | Autophagy | Indoleamine 2,3-Dioxygenase (IDO) | Ferroptosis
Molecular Weight 259.33
Appearance Solid
Synonyms Nec-1
SMILES O=C(C(CC1=CNC2=C1C=CC=C2)N3)N(C)C3=S
Purity 99.82%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years; 4°C/2 years
In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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