Neriifolin

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Cat. No.: IBDI-431042

Neriifolin, a CNS-penetrating cardiac glycoside, is an inhibitor of the Na +, K +-ATPase. Neriifolin can target beclin 1, inhibits the formation of LC3-associated phagosomes and ameliorates experimental autoimmune encephalomyelitis (EAE) development. Neriifolin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	Na+/K+ ATPase \| Apoptosis
Molecular Weight	534.68
Appearance	Solid
Synonyms	17β-Neriifolin
SMILES	O[[email protected]@]12[[email protected]@]3([H])[[email protected]@](CC[[email protected]@]1([[email protected]](C4=CC(OC4)=O)([H])CC2)C)([H])[[email protected]@]5([[email protected]](C[[email protected]](CC5)O[[email protected]]6[[email protected]]([[email protected]@H]([[email protected]]([[email protected]@H](O6)C)O)OC)O)([H])CC3)C
Structure Classification	Steroids>Cardiacglycosides
Purity	99.43%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.