Cat. No.: IBDA-431589
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Online InquiryTarget Information
Target Name | NLRP3 |
Uniprot ID | Q96P20 |
Cellular Localization | Cytoplasm. |
Immunogen | Recombinant fragment. |
Function | May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18. |
Product Details
Description | Rabbit monoclonal antibody to NLRP3 - BSA and Azide Free (Capture). |
Host Species | Rabbit |
Clonality | Monoclonal |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Mouse |
Immunogen | Recombinant fragment. |
Application | sELISA |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at 4 °C |
Storage Buffer | pH: 7.2 Constituent: 100% PBS |