NLRX1 Monoclonal Antibody - BSA and Azide Free

Target Information

Target Name	NLRX1
Uniprot ID	Q86UT6
Cellular Localization	Mitochondrion outer membrane.
Immunogen	Recombinant fragment.
Function	Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313).

Product Details

Description	Rabbit monoclonal antibody to NLRX1 - BSA and Azide Free.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Mouse, Human
Immunogen	Recombinant fragment.
Positive Control	WB: Wild-type HeLa whole, NLRX1 knockout HeLa whole, Mouse liver and Mouse heart lysates. IP: HeLa cell
Application	IP, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at 4 °C
Storage Buffer	pH: 7.20 Constituent: 100% PBS