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NPD-1335

Cat. No.: IBDI-436467

NPD1335 is a Trypanosoma brucei phosphodiesterase B1 (TbrPDEB1) inhibitor with submicromolar activities against T. brucei parasites. NPD1335 displays a greatly improved cytotoxicity profile. NPD1335 increases intracellular cAMP levels and results in the distortion of the cell cycle and cell death.

Size (Solid):

Product Details

Target PhosphodiesteRase (PDE) | PaRasite
Molecular Weight 455.55
Appearance Solid
SMILES O=C(NCC1=CC=CC=C1)C#CC2=CC(C3=NN(C(C)C)C([[email protected]@]4([H])CC=CC[[email protected]@]34[H])=O)=CC=C2OC
Purity 98.10%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years; 4°C/2 years
In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.