NSC 95397
Cat. No.: IBDI-437052
NSC 95397 is a potent, selective Cdc25 dual specificity phosphatase inhibitor (Ki=32 nM (Cdc25A), 96 nM (Cdc25B), 40 nM (Cdc25C); IC50=22.3 nM (human Cdc25A), 56.9 nM (human Cdc25C), 125 nM (Cdc25B)). NSC 95397 inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) and suppresses proliferation and induces apoptosis in colon cancer cells through MKP-1 and ERK1/2 pathway.
Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution
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Size (Solid):
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Product Details
| Target |
Phosphatase | Apoptosis |
| Molecular Weight |
310.39 |
| Appearance |
Solid |
| SMILES |
O=C1C(SCCO)=C(SCCO)C(C2=C1C=CC=C2)=O |
| Purity |
≥99.0% |
Storage & Handling
| Shipping |
Room temperature in continental US. May vary elsewhere. |
| Storage |
Powder: -20°C/3 years
In solvent: -80°C/6 months; -20°C/1 month |
| Regulatory Status |
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. |
! For research use only, not intended for any clinical use.
