NTQ1062

Cat. No.: IBDI-432626

NTQ1062 is a potent and orally active Akt inhibitor with IC50s of 0.4 nM, 6.3 nM and 0.1 nM for Akt1, Akt2 and Akt3, respectively. NTQ1062 induces cell apoptosis and arrests the cell cycle at G0/G1 phase. NTQ1062 exhibits antiproliferation activity against various cancer cells. NTQ1062 exhibits potent antitumor efficacy in LNCap xenograft mouse model.

Product Details

Target	Akt
Molecular Weight	483.01
SMILES	CC(C)NC[[email protected]](C1=CC=C(C=C1)Cl)C(N2[[email protected]@]3([H])[[email protected]@](C3)([H])N(C4=C5C(NC=N4)=NC(C[[email protected]]5C)=O)CC2)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.